Liver cirrhosis mortality at national and provincial levels in Iran between 1990 and 2015: A meta regression analysis |
Authors Negar
Rezaei, Mohsen Asadi-Lari, Ali Sheidaei, Sara Khademi, Kimiya Gohari,
Farnaz Delavari, Alireza Delavari, Elham Abdolhamidi, Maryam Chegini,
Nazila Rezaei, Hamidreza Jamshidi, Pegah Bahrami Taghanaki, Milad Hasan,
Moein Yoosefi, Farshad FarzadFar Publication date 2019/1/15 Publisher Public Library of Science Description Background
Liver cirrhosis mortality number has increased over the last decades.
We aimed to estimate the liver cirrhosis mortality rate and its trends
for the first time by sex, age, geographical distribution, and cause in
Iran. Method Iranian Death Registration System, along with demographic
(Complete and Summary Birth History, Maternal Age Cohort and Period
methods) and statistical methods (Spatio-temporal and Gaussian process
regression models) were used to address the incompleteness and
misclassification and uncertainty of death registration system to
estimate annual cirrhosis mortality rate. Percentages of deaths were
proportionally redistributed into cirrhosis due to hepatitis B, C and
alcohol use based on the data from the Global Burden of Disease (GBD)
2010 study. Results Liver cirrhosis mortality in elder patients was 12
times higher than that in younger patients at national level in 2015.
Over the 26 years, liver cirrhosis mortality in males has increased more
than that in females. Plus, the percentage of change in age adjusted
mortality rate at provincial levels varied between decreases of 64.53%
to nearly 17% increase. Mortality rate has increased until 2002 and then
decreased until 2015.The province with highest mortality rate in 2015
has nearly two times greater rate compare to the lowest. More than 60%
of liver cirrhosis mortality cases at national level are caused by
hepatitis B and C infection. The rate of hepatitis B mortality is four
times more than that from hepatitis C. Conclusion This study
demonstrated an increasing and then decreasing pattern in cirrhosis
mortality that could be due to national vaccination of hepatitis B …
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An Approach Towards Reducing Road Traffic Injuries and Improving Public Health Through Big Data Telematics: A Randomised Controlled Trial Protocol. |
Authors Mehrdad
Azmin, Ayyoob Jafari, Nazila Rezaei, Kavi Bhalla, Dipan Bose, Saeid
Shahraz, Mina Dehghani, Parastoo Niloofar, Soraya Fathollahi, Javad
Hedayati, Hamidreza Jamshidi, Farshad Farzadfar Publication date 2018/11/1 Journal Archives of Iranian Medicine (AIM) Description Objective:
Deaths due to road traffic accidents (RTAs) are a major public health
concern around the world. Developing countries are over-represented in
these statistics. Punitive measures are traditionally employed to lower
RTA related behavioural risk factors. These are, however, resource
intensive and require infrastructure development. This is a randomised
controlled study to investigate the effect of non-punitive behavioural
intervention through peer-comparison feedback based on driver behaviour
data gathered by an in-vehicle telematics device. Design, Setting, and
Participants: A randomised controlled trial using repeated measures
design conducted in Iran on the drivers of 112 public transport taxis in
Tehran province and 1309 inter-city busses operating nationwide.
Driving data is captured by an in-vehicle telematics device and sent to a
centrally located data centre using a mobile network. The telematics …
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Scientometric study on non-communicable diseases in Iran: A review article |
Authors Niloofar
Peykari, Hassan Hashemi, Gholamreza Asghari, Mohammadhadi Ayazi, Ghasem
Janbabaei, Reza Malekzadeh, Alireza Raeisi, Ali Sadrolsadat, Mohsen
Asadi-Lari, Aliasghar Farshad, Farshad Farzadfar, Mostafa Ghanei, Ali
Akbar Haghdoost, Ramin Heshmat, Hamidreza Jamshidi, Afshin Ostovar,
Amirhossein Takian, Bagher Larijani Journal Iranian journal of public health Publisher Tehran University of Medical Sciences Description Background: Non-Communicable
disease (NCDs) is a killer of people that needs to urgent actions
across the world. Scientific evidence is the critical arm for effective
interventions. Therefore, we aimed to quantify the trend of four main
NCDs’ scientific publication in a 17-yr period, and reflect
international collaboration. Methods: This
scientometric study on four main NCDs; cardiovascular diseases,
cancers, diabetes, and chronic respiratory diseases were carried out
through the narrative review in international databases of Scopus from
2000 to 2016. In this way, the number of articles, citations, and
international collaboration were assessed, and the frequently used terms
on noncommunicable diseases were mapped by VOSviewer software. Results: Over
the 17 years, 25827 articles about four main NCDs by Iran indexed in
Scopus have increasing trend steadily. However, chronic obstructive
respiratory publications …
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Umbelliprenin shows antitumor, antiangiogenesis, antimetastatic, anti‐inflammatory, and immunostimulatory activities in 4T1 tumor‐bearing Balb/c mice |
Authors Mohsen Rashidi, Ahad Khalilnezhad, Davar Amani, Hamidreza Jamshidi, Ahad Muhammadnejad, Ali Bazi, Seyed Ali Ziai Publication date 2018/5/24 Journal journal of cellular physiology Description Umbelliprenin
(UMB) has shown various pharmacological properties in vitro. We
investigated the antineoplastic and immunostimulatory effects of UMB in
4T1 mammary‐tumor‐bearing mice. Two‐hundred microliter of UMB
(12.5 mg/ml) was intraperitoneally administrated to healthy and
tumor‐bearing female Balb/c mice for a period of 18 days. Data was
analyzed using GraphPad Prism 5 software for Windows (version 5, La
Jolla, CA). UMB caused a significant decrease in tumor size (P < 0.01). Serum interferon gamma (IFNγ) was augmented in both healthy and tumor‐bearing animals (P < 0.01), and IL‐4 declined in healthy animals (P < 0.01)
treated with UMB. Expressions of Ki‐67, VEGF, CD31, MMP2, MMP9, VCAM1,
and NF‐κB were significantly decreased in tumors from UMB‐treated
animals (P < 0.001), whereas E‐Cadherin and TNFR1 expressions were markedly increased (P < 0.001). The … Scholar articles M Rashidi, A Khalilnezhad, D Amani, H Jamshidi… - Journal of Cellular Physiology, 2018 dfsdfsdfsdfsd
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Attenuation of Diabetic Nephropathy by Carvacrol through Anti-oxidative Effects in Alloxan-Induced Diabetic Rats |
Authors Hamid Reza Jamshidi, Zahra Zeinabady, Ehsan Zamani, Mohammad Shokrzadeh, Fatemeh Shaki Publication date 2018/3/12 Journal Research Journal of Pharmacognosy Publisher -The Iranian Society Pharmacognoy-Shahid Beheshti University of Medical Sciences Description Background and Objectives:
Diabetes, a common metabolic disorder, is prevalent in many countries.
Nephropathy is a main debate’s side effect. Role of oxidative stress is
well known in induction of diabetic nephropathy while carvacrol is a
potent anti-oxidant that might attenuate oxidative stress. The aim of
this study was to explore the effect of carvacrol in decreasing
nephropathy-induced oxidative damage in diabetic rats. Methods:
Thirty five Wistar rats (200-250 g) were divided to 7 groups. The rats
received alloxan (ip, 200 mg/kg) for induction of diabetes. After one
week, fasting blood sugar (FBS) was assessed and the rats with FBS>
250 mg/dL were considered as diabetic. Three weeks after alloxan
injection, the blood urea (BUN) and creatinine (Cr) were determined for
confirmation of inducing nephropathy. Then, the animals were treated
with carvacrol for one week. Finally, they were anesthetized and blood
was collected from animal’s heart for calculation of BUN and Cr.
Furthermore, the kidneys were for oxidative stress markers such as
glutathione capacity, protein carbonyl, lipid peroxidation and catalase
activity. Results:
Our results showed that glutathione level and catalase activity
significantly increased after treatment with carvacrol. Same results
were found in rats that received vitamin E. Also, lipid peroxidation,
protein carbonyl content, BUN and Cr levels significantly decreased
after treatment with carvacrol in comparison with diabetic rats. Conclusion:
Our results showed that carvacrol improved nephropathyinduced oxidative
damage similar to vitamin E. Therefore, it may be suggested that
carvacrol can be suggested as a useful …Scholar articles HR Jamshidi, Z Zeinabady, E Zamani, M Shokrzadeh… - Research Journal of Pharmacognosy, 2018
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Impact of rural family physician program on child mortality rates in Iran: a time-series study |
Authors Shohreh
Naderimagham, Hamidreza Jamshidi, Alireza Khajavi, Farhad Pishgar, Ali
Ardam, Bagher Larijani, Zohreh Mahmoudi, Alireza Jeddian, Hamid Reza
Bahrami-Taghanaki, Farshad Farzadfar Journal Population health metrics Description The
rural family physician program and social protection scheme were
started in Iran about 10 years ago, and no comprehensive study has been
carried out to investigate the effects of this program on
mortality-related health indicators yet. The present study aims to
examine the impacts of implementation of the family physician program
and rural insurance program, which was launched in June 2005, on
neonatal (NMR), infant (IMR), and under-5-year (U5MR) mortality rates in
rural areas of Iran between 1995 and 2011, using a time-series
analysis. Three segmented regression models were built to evaluate the
effects of the program on NMR, IMR, and U5MR, and several independent
variables were entered into the models, including annual incremental
effect of the program (variable of interest), time effect, behvarz
density, effect of the family physician and rural insurance programs, as
well as socioeconomic variables including years of schooling, wealth
index, sex ratio, and logarithmic scales of rural population size in
each area. Data were gathered from secondary sources and other studies.
Data pertaining to the year 2007 were excluded from the final analysis
due to their inaccuracy. Our results show that the incremental effect of
implementing the rural family physician program is associated with
significant reductions in NMR (β = − 0.341. p − value = 0.003) and IMR
(β = − 0.016. p − value = 0.009). Although the association between this
effect and reductions in U5MR were evident, they were not statistically
significant (β = − 0.003. p − value = 0.542). Moreover, wealth status of
inhabitants was associated with reductions in … Scholar articles S Naderimagham, H Jamshidi, A Khajavi, F Pishgar… - Population health metrics, 2017
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National action plan for non-communicable diseases prevention and control in Iran; a response to emerging epidemic |
Authors Niloofar
Peykari, Hassan Hashemi, Rasoul Dinarvand, Mohammad Haji-Aghajani, Reza
Malekzadeh, Ali Sadrolsadat, Ali Akbar Sayyari, Mohsen Asadi-Lari,
Alireza Delavari, Farshad Farzadfar, Aliakbar Haghdoost, Ramin Heshmat,
Hamidreza Jamshidi, Naser Kalantari, Ahmad Koosha, Amirhossein Takian,
Bagher Larijani Source Journal of Diabetes & Metabolic Disorders Description Emerging
Non-communicable diseases burden move United Nation to call for 25%
reduction by 2025 in premature mortality from non-communicable diseases
(NCDs). The World Health Organization (WHO) developed global action plan
for prevention and control NCDs, but the countries’ contexts,
priorities, and health care system might be different. Therefore, WHO
expects from countries to meet national commitments to achieve the 25 by
25 goal through adapted targets and action plan. In this regards,
sustainable high-level political statement plays a key role in rules and
regulation support, and multi-sectoral collaborations to NCDs’
prevention and control by considering the sustainable development goals
and universal health coverage factors. Therefore, Iran established the
national authority’s structure as Iranian Non Communicable Diseases
Committee (INCDC) and developed NCDs’ national action plan through
multi-sectoral approach and collaboration researchers and policy makers.
Translation Iran’s expertise could be benefit to mobilizing leadership
in other countries for practical action to save the millions of peoples. Scholar articles N Peykari, H Hashemi, R Dinarvand, M Haji-Aghajani… - Journal of Diabetes & Metabolic Disorders, 2017
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Effects of parathion on the activity of mitochondrial glutamate dehydrogenase from rat pancreatic Langerhans islets |
Authors Hamid Reza Jamshidi, Elham Ebrahimi, Ali Moradi Publication date 2017/10/20 Journal Toxicology Letters Description The
main propose of the present study was to determine the effects of
parathion on the activity of glutamate dehydrogenase (GDH) as the key
enzyme of Langerhans islet for secretion of insulin. Parathion was
administered intraperitoneally at doses of 0.5, 1, 1.5 and 2 mg/kg.
Langerhans islets were isolated from the pancreas of rats by a standard
collagenase digestion, separation by centrifugation, and hand-picking
technique. The activity of the mitochondrial GDH was determined in the
islets homogenates. Parathion at tested doses (0.5, 1) had no effect on
GDH secretion but at doses of 1.5 and 2 mg/kg significantly (p< 0.05)
increased production of glutamate after 4 days treatment. It is
concluded that GDH is a component of parathion-induced changes in
release of improper insulin. It might be said parathion can increase
production of glutamate that increase secretion of insulin but this
insulin is not enough to … Scholar articles HR Jamshidi, E Ebrahimi, A Moradi - Toxicology Letters, 2017
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Measuring Iran's success in achieving Millennium Development Goal 4: a systematic analysis of under-5 mortality at national and subnational levels from 1990 to 2015 |
Authors Younes
Mohammadi, Mahboubeh Parsaeian, Parinaz Mehdipour, Ardeshir Khosravi,
Bagher Larijani, Ali Sheidaei, Anita Mansouri, Amir Kasaeian, Kamran
Yazdani, Maziar Moradi-Lakeh, Elaheh Kazemi, Saeide Aghamohamadi, Nazila
Rezaei, Maryam Chegini, Rosa Haghshenas, Hamidreza Jamshidi, Farnaz
Delavari, Mohsen Asadi-Lari, Farshad Farzadfar Journal The Lancet Global Health Description BackgroundChild
mortality as one of the key Millennium Development Goals (MDG 4—to
reduce child mortality by two-thirds from 1990 to 2015), is included in
the Sustainable Development Goals (SDG 3, target 2—to reduce child
mortality to fewer than 25 deaths per 1000 livebirths for all countries
by 2030), and is a key indicator of the health system in every country.
In this study, we aimed to estimate the level and trend of child
mortality from 1990 to 2015 in Iran, to assess the progress of the
country and its provinces toward these goals. MethodsWe
used three different data sources: three censuses, a Demographic and
Health Survey (DHS), and 5-year data from the death registration system.
We used the summary birth history data from four data sources (the
three censuses and DHS) and used maternal age cohort and maternal age
period methods to estimate the trends in child mortality rates,
combining the … Scholar articles Y Mohammadi, M Parsaeian, P Mehdipour, A Khosravi… - The Lancet Global Health, 2017
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Involvement of Different Protein Kinases in Transmitter Mobilization during Repetitive Stimulation |
Authors Hamidreza Jamshidi, Mohsen Rashidi, MojtabaHaghi Karramallah Journal INTERNATIONAL JOURNAL OF ADVANCED BIOTECHNOLOGY AND RESEARCH Publisher BIOIT INTERNATIONALJOURNALS Description Evidence
of involvement of different ProteinKinase (PK) on mobilization of
releasable vesicle is not yet firm. This study was conducted to assess
the involvement of different protein kinases in mobilization process.
The hemidiaphragm-phernic nerve of ICR Strain mouse were dissected free
and pinned to the sylgard. Tissues were bathed in oxygenated 18mM
Hepes-buffered Bretags synthetic interstitial fluid. Muscle fiber distal
to a strip extending to 3 mm on either side of phernic nerve branches
was cut and residual central innervated strip was used. Muscle action
potential was blocked. Bretag's solution was perfused. Rate and extent
of End Plate Potentials (EPP) was recorded. The mean amplitude of EPPs
was calculated. Effect of different drugs on EPP rundown in comparison
with control in three and four separate preparations were recorded, and
the percentage of initial EPP against time was plotted. The main … Scholar articles H Jamshidi, M Rashidi, MH Karramallah - INTERNATIONAL JOURNAL OF ADVANCED …, 2017
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National and subnational patterns of cause of death in Iran 1990-2015: applied methods |
Authors Kimiya Gohari, Nazila Rezaei, MD Farshad Farzadfar Journal Archives of Iranian medicine Publisher Academy of Medical Sciences of IR Iran Description Background:
Causes of death statistics provide crucial health intelligence in
national and international communities. An efficient death registration
system provides reliable information for health policy system. In many
developing countries, death registration systems face a degree of
misclassification and incompleteness. There are many impediments to
putting an estimate of cause-specific death rates. Addressing
those challenges could prevent misleading results. Methods: Our data
was collected by Ministry of Health and Medical Education, Tehran and
Isfahan cemeteries from 1995 to 2010. After converting ICD codes of
Iran’s death registration into GBD codes, 170 underlying causes of
deaths were recognized in the available data. A wide range of methods
were applied for preparing the data. We used several statistical models
to estimate mortality rates in agesex-province groups for all causes of
deaths. The considerable number of combinations for age, sex, cause of
death, year, and province Scholar articles K Gohari, N Rezaei, MD Farshad Farzadfar - Archives of Iranian medicine, 2017
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Evaluating cytotoxic effect of nanoliposomes encapsulated with umbelliprenin on 4T1 cell line |
Authors Mohsen Rashidi, Alireza Ahmadzadeh, Seyed Ali Ziai, Mahsa Narenji, Hamidreza Jamshidi Journal In Vitro Cellular & Developmental Biology-Animal Description Cytotoxicity
of umbelliprenin has been found in various cancer cell lines such as,
prostate, breast, CLL, and skin. Encapsulating chemotherapeutic agents
with nanoliposomes have been resulted in improved cytotoxicity effects
than their free forms. However, whether nanoliposomal form of
umbelliprenin could have higher cytotoxic effect than free umbelliprenin
is not clarified yet. After synthesizing umbelliprenin, different
concentrations (3, 6, 12, 25, 50, 100, 200 μg/ml) applied on the mouse
mammary carcinoma cell line (4T1) for 24, 48, and 72 h at 37°C.
Afterwards, the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium
bromide (MTT) assay was performed to analyze cytotoxicity. MTT assay
results showed that IC50 of umbelliprenin in dimethyl
sulfoxide (DMSO) (30.92, 30.64, and 62.23 for 24, 48, 72 h incubation,
respectively) decreased (5.8, 5.0, 3.5 for 24, 48, 72 h incubation,
respectively) when … Scholar articles M Rashidi, A Ahmadzadeh, SA Ziai, M Narenji… - In Vitro Cellular & Developmental Biology-Animal, 2017
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Birth seasonality in rural areas of Iran, analysis of 5,536,262 births from 1992 to 2007 |
Authors Alireza
Khajavi, Farhad Pishgar, Mahboubeh Parsaeian, Sahar Saeedi Moghaddam,
Alireza Jeddian, Hamid Reza Bahrami-Taghanaki, Hamid Reza Jamshidi,
Shohreh Naderimagham Publication date 2016/12/1 Journal Annals of epidemiology Description PurposeWe conducted this study to investigate birth seasonality in rural parts of Iran. MethodsIn
this study, patterns of 5,536,262 live births in rural parts of Iran
between 1992 and 2007 were studied. Information about birth numbers,
environmental factors, and sociocultural status of participants was
obtained from previous works. Visually inspecting the seasonal variation
of birth, studying its trend using autocorrelation analysis, examining
the trend of birth seasonality using the seasonality coefficient, a
newly introduced index, studying correlations between birth seasonality
and possible associated factors, and analyzing associations between
these variables and birth seasonality using multiple regression model
were performed in this study. ResultsIn
this study, we showed birth seasonality in rural parts of Iran, with
the highest births in the first two seasons, winter and spring, mostly
before the year of 2002. Latitude and … Scholar articles A Khajavi, F Pishgar, M Parsaeian, SS Moghaddam… - Annals of epidemiology, 2016
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Tax Audits Based on Risk-Based Audit Approaches |
Authors Hokmabadi Ali Shiri, HAMID JAMSHIDI, NILOUFAR MIRSEPASI Publisher ACCOUNTING RESEARCH Description Importance
as a major source of state income tax, known to everybody, accordingly
tax audits, and to consider the effectiveness, efficiency and economy of
tax audit process and the role and adequacy of internal controls in
this regard, due to the complex business environment over it is
important to use the audit risk model as a solution to a tax audit is
taken into consideration. This research is on adaptability of the
risk-based audit model aims to address the risks identified in the
census sample handling and how to calculate the relationship between the
identified risks and determine the actual tax rate. Results of the
sampling theory are also indicated to reduce the risk, the adequacy of
the audit model variables and only on the assumption that the
effectiveness of the model resultsTest the adequacy and
comprehensiveness of the model in order to coverall topics addressed in
the balance sheet and profit and loss statement shows. Scholar articles HA Shiri, H JAMSHIDI, N MIRSEPASI - 2018
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The most prevalent causes of deaths, DALYs, and geriatric syndromes in Iranian elderly people between 1990 and 2010: findings from the global burden of disease study 2010 |
Authors MD Farshad Sharifi, Alireza Delavari Journal Archives of Iranian medicine Publisher Academy of Medical Sciences of IR Iran Description Background:
The substantial increase in life expectancy during recent decades has
left all countries with a high number of elderly people that have
particular health needs. Health policy-makers must be aware of the most
prevalent causes of deaths and DALYs in this age group, as well as
geriatric syndromes, in order to provide appropriate care and allocate
resources in an equitable manner. Methods: The
Global Burden of Disease study 2010 (the GBD study 2010), conducted by
the Institute for Health Metrics and Evaluation team, estimated the
worldwide burden of diseases from 1990 to 2010. Its estimations were
conducted on the basis of the proportion of deaths, the duration of
symptoms and disability weights for sequelae, years lived with
disability (YLDs), years of life lost (YLLs), and disability adjusted
life years (DALYs) attributable to different diseases. In the present
study, we extracted the data regarding the … Scholar articles MD Farshad Sharifi, A Delavari - Archives of Iranian medicine, 2015
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Tobacco Smoking Status and the Contribution to Burden of Diseases in Iran, 1990-2010: findings from the Global Burden of Disease Study 2010. |
Authors Anoosheh
Ghasemian, Nazila Rezaei, Sahar Saeedi Moghaddam, Anita Mansouri,
Mahboubeh Parsaeian, Alireza Delavari, Hamid Reza Jamshidi, Farshad
Sharifi, Shohreh Naderimagham Journal Archives of Iranian Medicine (AIM) Description Background:
Tobacco smoking and exposure to second-hand smoke in the indoor
environment are major public health risks worldwide. The aim of this
paper is to report and critique a global assessment of smoking
prevalence, smoking-attributable deaths, and disability adjusted life
years (DALYs) extracted from the Global Burden of Disease study 2010, by
sex and age in Iran from 1990 to 2010. Methods: The Global Burden of
Disease Study 2010 estimated the distributions of exposure and relative
risks per unit of exposure by systematically reviewing and analyzing
published and unpublished data. These assessments were used, together
with estimates of death and DALYs due to specific risk factors, to
calculate the attributed burden for each risk factor exposure compared
with the theoretical-minimum-risk exposure. Uncertainties in the
distribution of exposure, relative risks, and relevant outcomes were … Scholar articles A Ghasemian, N Rezaei, SS Moghaddam, A Mansouri… - Archives of Iranian Medicine (AIM), 2015
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A Single Period Multi Objective Mathematical Model for Portfolio |
Authors MEHDI ABZARI, AHMAD DADASHPOR, MEHDI KHALILI, HAMID JAMSHIDI Publisher PRODUCTION AND OPERATIONS MANAGEMENT Description Optimal
portfolio selection and how to invest in, is one of the key issues
which is considered in the capital market and should be paid attention
by investors. In this regard, investors studies in selecting optimal
portfolio accords to risk and return level. What has been done in the
field of financial calculations and portfolio selection should
prioritize existing investments in terms of risk and return
respectively, until investors be able to constitute their optimal
portfolio according to the finance and their level of risk-taking.
Hence, measuring risk is considered as a major issue in the investment
of portfolio. So in this research which was done in a capital market of
Iran, it is presented a multi objective single-period mathematical model
for measuring the risk of portfolio which integrates measure of return
and two measures of risk (semivariance, Cvar). This model enables
investors to measure the risk of portfolio carefully under transactions
cost constrains and invest in a portfolio with maximum rate of return
and minimum rate of risk Results show that using integraed risk measure
can increase the carefulness of investors in capital market for optimal
portfolio selection. Scholar articles M ABZARI, A DADASHPOR, M KHALILI, H JAMSHIDI - 2015
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Burden of Cancers in Iran from 1990 to 2010: findings from the Global Burden of Disease study 2010 |
Authors Mitra
Modirian, Shadi Rahimzadeh, Zahra Cheraghi, MOGHADDAM SAHAR SAEEDI,
Nazila Rezaei, Hamid Reza Tohidinik, Amir Kasaeian, Hamid Reza Jamshidi,
Roya Ghobadi, Farzad Kompani Publisher ARCHIVES OF IRANIAN MEDICINE Description Background:
Cancer is one of the most common non-communicable diseases in both
sexes and a major cause of disability and death around the world, as
well as in Iran. The aim of the present manuscript is to report the
results of the Global Burden of Disease study 2010 (the GBD 2010) to
compare them with other similar findings. The paper also discusses the
current deficiencies in the GBD study. Our aim was to describe and
criticize the attributed burden of cancers according to the GBD results
by sex and age. Methods: The GBD 2010 has
profited from 100 collaborators worldwide and provides a vast network of
data on health outcomes, vital registries, and population surveys. The
GBD has used various scientific-approved methods to estimate important
health statuses like death rates, life expectancy, and healthy adjusted
life expectancy, disability-adjusted life years, years of living lost
due to premature death and years of life with disabilities. In the
present study, we extracted and graphed the GBD results for Iran in
order to present a better scheme for readers. Results: The mortality
rate of cancers in Iranians has increased by about 8.5%, while the
disability-adjusted life year rates have declined by about 9%, and years
lost due to premature death have also decreased by about 10% from 1990
to 2010 compared to an 85% increase in years of life with disabilities
in the same time period. Conclusion: The
burden of all non-communicable diseases (NCDs) including cancers shows a
decrease during the past two decades. However, these diseases still
remain a global health challenge. Prevention should be considered as an
important priority and … Scholar articles M Modirian, S Rahimzadeh, Z Cheraghi, MS SAEEDI… - 2015
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National and sub-national prevalence, trend, and burden of end stage renal diseases (ESRD) in Iran 1990-2013; the study protocol |
Authors Tahereh Hassannia, Farnaz Delavari Publication date 2014/12/1 Journal Archives of Iranian medicine Publisher Academy of Medical Sciences of IR Iran Description Background:
End Stage Renal Diseases (ESRD) imposes a huge economic burden on the
health system; however, there is a serious lack of data related to ESRD,
especially at Sub-national level, in Iran. Calculating the burden of
ESRD at National and Sub-national level provides an opportunity to apply
cost-effective interventions for the purpose of prevention and
treatment. The current study protocol aims to explain the general
structure and methods that will be used in the burden of ESRD study in
Iran from 1990 to 2013. Methods: The prevalence, incidence, mortality
and geographical and socioeconomic inequality trend of ESRD will be
calculated through a comprehensive systematic review of published and
unpublished data. Years of Life Lost due to premature mortality, and
Years Lived with Disability and Disability-Adjusted Life Years (DALYs)
will be quantified for ESRD by gender, age group, and province with
their uncertainly intervals.“Spatio-Temporal” and “Bayesian multilevel
autoregressive” will be applied to deal with data scarcity and
misalignment problem which exist in the data sources. Discussion:
The findings of the burden of ESRD study will be useful to organize
preventive, treatment also research priorities at national and
sub-national levels in Iran. Better understanding of the magnitude of
ESRD burden is essential to prevent the progression of chronic kidney
diseases to the end stage phase which is considered as a devastating
illness. Scholar articles T Hassannia, F Delavari - Archives of Iranian medicine, 2014
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